Danila Moscone is full professor at the Dipartimento di Scienze e Tecnologie Chimiche of the Università degli Studi di Roma Tor Vergata. Her activity concerns the construction of different biosensors and its application in analytical matrices since thirty years. During this time she improved her experience in the field of electrochemical sensors and flow systems coupled to biosensors. In particular, she is an expert in enzymes immobilization on polymer matrices and in sensors and biosensors miniaturization. For many years she was involved in European projects on continuous and real-time in vivo measurement, developing new miniaturized biosensors for glucose and coupling for the first time biosensors with innovative sampling techniques such as microdialysis and ultrafiltration, both in clinical field and in foods analysis and quality control. In recent years she worked in projects funded by the European Community, for the development of immunosensors and biosensors based on screen printed disposable electrodes, for the realization of single-use immunosensor for toxins (mycotoxins in milk and cereals, bacterial toxins and phycotoxins in foods) and bacteria (Staphylococcus aureus, Salmonella, etc..); for rapid and innovative analytical methods for the analysis and control of GMOs, and had contracts with private companies (Menarini for the realization of printed sensors for continuous monitoring of glucose). Other applications have been the realization of highly selective biosensors based on printed electrodes modified with Prussian Blue, biosensors for the determination of pesticides based on enzyme inhibition, realization of systems in flow for the determination of nitrites and nitrates and realization of potentiometric microsensors for pH, potassium, calcium, ammonium, nitrate, for the protection and preservation of cultural heritage. New projectsunderway are the development of immunosensor for the determination of antibodies and metabolites of clinical interest (IgA, IgE, lactate ... ) in biological matrices such as serum and saliva, of electrochemical biosensors based on DNA (eDNA ) for the determination of protein and transcription factors and of sensors and biosensors modified withnanostructured material. Her more recent interests concern sensors modification with nanomaterials and realization of “all-in-one” paper-based electrochemical devices.
